Chapter 13. Nuclear Receptors as Targets in Cardiovascular Diseases

  1. Prof. Dr. Eckhard Ottow3 and
  2. Dr. Hilmar Weinmann4
  1. Peter Kolkhof1,
  2. Lars Bärfacker2,
  3. Alexander Hillisch2,
  4. Helmut Haning2 and
  5. Stefan Schäfer1

Published Online: 19 DEC 2008

DOI: 10.1002/9783527623297.ch13

Nuclear Receptors as Drug Targets

Nuclear Receptors as Drug Targets

How to Cite

Kolkhof, P., Bärfacker, L., Hillisch, A., Haning, H. and Schäfer, S. (2008) Nuclear Receptors as Targets in Cardiovascular Diseases, in Nuclear Receptors as Drug Targets (eds E. Ottow and H. Weinmann), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527623297.ch13

Editor Information

  1. 3

    Bayer Schering Pharma AG, Medicinal Chemistry (S106/345), Müllerstrasse 178, 13342 Berlin, Germany

  2. 4

    Bayer Schering Pharma AG, Medicinal Chemistry (S106/048A), Müllerstrasse 178, 13342 Berlin, Germany

Author Information

  1. 1

    Bayer Schering Pharma AG, Institute for Cardiology Research, Aprather Weg 18a, 42096 Wuppertal, Germany

  2. 2

    Bayer Schering Pharma AG, Medicinal Chemistry Europe, Aprather Weg 18a, 42096 Wuppertal, Germany

Publication History

  1. Published Online: 19 DEC 2008
  2. Published Print: 20 AUG 2008

Book Series:

  1. Methods and Principles in Medicinal Chemistry

Book Series Editors:

  1. Prof. Dr. Raimund Mannhold5,
  2. Prof. Dr. Hugo Kubinyi6 and
  3. Prof. Dr. Gerd Folkers7

Series Editor Information

  1. 5

    Molecular Drug Research Group, Heinrich-Heine-Universität, Universitätsstrasse 1, 40225 Düsseldorf, Germany

  2. 6

    Donnersbergerstrasse 9, 67256 Weisenheim am Sand, Germany

  3. 7

    Collegium Helveticum, STW/ETH Zurich, 8092 Zurich, Switzerland

ISBN Information

Print ISBN: 9783527318728

Online ISBN: 9783527623297

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Keywords:

  • mineralocorticoid receptor;
  • thyroid hormone receptors;
  • peroxisome proliferator-activated receptor α;
  • heart failure

Summary

This chapter contains sections titled:

  • Introduction

  • MR (NR3C2)

  • THRs (NR1A1 and NR1A2)

  • PPARα (NR1C1)

  • VDR (NR1I1)

  • Retinoic Acid Receptors (NR1B1, 2 and 3) and Retinoid X Receptors (NR2B1, 2 and 3)

  • Liver X Receptors (NR1H3 and NR1H2)

  • Outlook

  • References