Chapter 3. Untangling the Estrogen Receptor Web: Tools to Selectively Study Estrogen-Binding Receptors

  1. Prof. Dr. Eckhard Ottow2,
  2. Dr. Hilmar Weinmann3
  1. Ross V. Weatherman

Published Online: 19 DEC 2008

DOI: 10.1002/9783527623297.ch3

Book Title

Nuclear Receptors as Drug Targets

Nuclear Receptors as Drug Targets

Additional Information

How to Cite

Weatherman, R. V. (2008) Untangling the Estrogen Receptor Web: Tools to Selectively Study Estrogen-Binding Receptors, in Nuclear Receptors as Drug Targets (eds E. Ottow and H. Weinmann), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527623297.ch3

Editor Information

  1. 2

    Bayer Schering Pharma AG, Medicinal Chemistry (S106/345), Müllerstrasse 178, 13342 Berlin, Germany

  2. 3

    Bayer Schering Pharma AG, Medicinal Chemistry (S106/048A), Müllerstrasse 178, 13342 Berlin, Germany

Author Information

  1. Purdue University, Department of Medicinal Chemistry and Molecular Pharmacology, 575 Stadium Mall Drive, West Lafayette, IN 47907, USA

Publication History

  1. Published Online: 19 DEC 2008
  2. Published Print: 20 AUG 2008

Book Series:

  1. Methods and Principles in Medicinal Chemistry

Book Series Editors:

  1. Prof. Dr. Raimund Mannhold4,
  2. Prof. Dr. Hugo Kubinyi5,
  3. Prof. Dr. Gerd Folkers6

Series Editor Information

  1. 4

    Molecular Drug Research Group, Heinrich-Heine-Universität, Universitätsstrasse 1, 40225 Düsseldorf, Germany

  2. 5

    Donnersbergerstrasse 9, 67256 Weisenheim am Sand, Germany

  3. 6

    Collegium Helveticum, STW/ETH Zurich, 8092 Zurich, Switzerland

ISBN Information

Print ISBN: 9783527318728

Online ISBN: 9783527623297

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CHAPTER TOOLS

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Keywords:

  • estrogen receptor;
  • estrogen-binding receptors

Summary

This chapter contains sections titled:

  • Physiological Roles of Estrogen and the Challenges in Drug Discovery

  • Possibility of Multiple Targets

  • ERα

  • ERβ

  • ERR

  • GPR30

  • Membrane ERs

  • Integrated Estrogen Signaling

  • Conclusions

  • References

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