Chapter 10. The Role of Endothelium

  1. Prof. Dr. Jean-Marc Cavaillon3 and
  2. Dr. Christophe Adrie4
  1. Siew-Yean Lau1 and
  2. Fumito Ichinose2

Published Online: 25 MAY 2009

DOI: 10.1002/9783527626151.ch10

Sepsis and Non-Infectious Systemic Inflammation: From Biology to Critical Care

Sepsis and Non-Infectious Systemic Inflammation: From Biology to Critical Care

How to Cite

Lau, S.-Y. and Ichinose, F. (2008) The Role of Endothelium, in Sepsis and Non-Infectious Systemic Inflammation: From Biology to Critical Care (eds J.-M. Cavaillon and C. Adrie), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527626151.ch10

Editor Information

  1. 3

    Unit Cytokines et Inflammation, Institut Pasteur, 28, rue Dr. Roux, 75015 Paris, France

  2. 4

    Hôpital Delafontaine, Réanimation Polyvalente, 2 rue du Docteur Delafontaine, 93205 Saint-Denis, France

Author Information

  1. 1

    Harvard Medical School, Massachusetts General Hospital, Anesthesia Center for Critical, Care Research, Charlestown, USA

  2. 2

    Massachusetts General, Hospital/Harvard Medical School, Anesthesia Center for Critical Care Research, Charlestown, USA

Publication History

  1. Published Online: 25 MAY 2009
  2. Published Print: 15 OCT 2008

ISBN Information

Print ISBN: 9783527319350

Online ISBN: 9783527626151

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Keywords:

  • endothelium;
  • coagulation;
  • nitric oxide;
  • procoagulant microparticles;
  • vasodilator;
  • vasoconstictor;
  • therapeutic target

Summary

This chapter contains sections titled:

  • Introduction

  • Endothelial Cell Functions and their Changes in SIRS and Sepsis

  • Endothelium-centered Therapeutic Approaches in Severe Sepsis

  • Role of Endothelium and Future Therapeutic Challenges in Sepsis and SIRS

  • References