Chapter 17. The Past, Present and Future of Therapies for Sepsis and Non-Infectious Systemic Inflammation

  1. Prof. Dr. Jean-Marc Cavaillon2,
  2. Dr. Christophe Adrie3
  1. Nitin Seam,
  2. Anthony F. Suffredini

Published Online: 25 MAY 2009

DOI: 10.1002/9783527626151.ch17

Book Title

Sepsis and Non-Infectious Systemic Inflammation: From Biology to Critical Care

Sepsis and Non-Infectious Systemic Inflammation: From Biology to Critical Care

Additional Information

How to Cite

Seam, N. and Suffredini, A. F. (2009) The Past, Present and Future of Therapies for Sepsis and Non-Infectious Systemic Inflammation, in Sepsis and Non-Infectious Systemic Inflammation: From Biology to Critical Care (eds J.-M. Cavaillon and C. Adrie), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527626151.ch17

Editor Information

  1. 2

    Unit Cytokines et Inflammation, Institut Pasteur, 28, rue Dr. Roux, 75015 Paris, France

  2. 3

    Hôpital Delafontaine, Réanimation Polyvalente, 2 rue du Docteur Delafontaine, 93205 Saint-Denis, France

Author Information

  1. National Institutes of Health, Critical Care Medicine Department, Bethesda, USA

Publication History

  1. Published Online: 25 MAY 2009
  2. Published Print: 15 OCT 2008

ISBN Information

Print ISBN: 9783527319350

Online ISBN: 9783527626151

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Keywords:

  • Circulatory shock;
  • acute inflammation;
  • immunotherapy;
  • corticosteroids;
  • anticoagulant therapy

Summary

This chapter contains sections titled:

  • Introduction

  • Historical Elements in the Treatment of Infection

  • Historical Elements in the Treatment of Inflammation Associated with Infection or Injury

  • Historical Developments in the Treatment of Shock

  • Contemporary Developments in Sepsis and Non-infectious Systemic Inflammation: the Molecular Basis of Inflammation associated with Infection and Shock

  • Endotoxin as a Therapeutic Target

  • Immunotherapy Revisited

  • Anti-Inflammatory Approaches to Sepsis and Systemic Inflammation

  • Resurrecting the Use of Corticosteroids in Sepsis

  • The Role of Anti-coagulant Therapy in Sepsis

  • Immunostimulatory Therapies for Sepsis and Shock

  • Contemporary Therapy for Infection and Shock

  • The Future of Therapies for Sepsis and Non-infectious Systemic Inflammation

  • References

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