Chapter 1. Molecular Mechanisms of Cancer Induction and Chemoprevention

  1. Prof. Dr. Siegfried Knasmüller1,
  2. Dr. David M. DeMarini2,
  3. Prof. Ian Johnson3 and
  4. Dr. Clarissa Gerhäuser4,5
  1. Helmut Bartsch5 and
  2. Dr. Clarissa Gerhäuser4,5

Published Online: 16 JUL 2009

DOI: 10.1002/9783527626588.ch1

Chemoprevention of Cancer and DNA Damage by Dietary Factors

Chemoprevention of Cancer and DNA Damage by Dietary Factors

How to Cite

Bartsch, H. and Gerhäuser, C. (2009) Molecular Mechanisms of Cancer Induction and Chemoprevention, in Chemoprevention of Cancer and DNA Damage by Dietary Factors (eds S. Knasmüller, D. M. DeMarini, I. Johnson and C. Gerhäuser), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527626588.ch1

Editor Information

  1. 1

    Medical University of Vienna, Department of Medicine I, Institute of Cancer Research, Borschkegasse 8a, 1090 Vienna, Austria

  2. 2

    U.S. Environmental Protection Agency, Environmental Carcinogenesis Division, Research Triangle Park, NC 27711, USA

  3. 3

    Institute of Food Research, Intestinal Biology and Health Programme, Norwich Research Park, Colney, Norwich NR4 7UA, UK

  4. 4

    German Cancer Research Centre (DKFZ), Toxicology and Cancer Risk Factors, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany

  5. 5

    German Cancer Research Center, Division of Epigenomics and Cancer Risk Factors, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany

Author Information

  1. 4

    German Cancer Research Centre (DKFZ), Toxicology and Cancer Risk Factors, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany

  2. 5

    German Cancer Research Center, Division of Epigenomics and Cancer Risk Factors, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany

Publication History

  1. Published Online: 16 JUL 2009
  2. Published Print: 25 MAR 2009

ISBN Information

Print ISBN: 9783527320585

Online ISBN: 9783527626588

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Keywords:

  • angiogenesis;
  • apoptosis;
  • carcinogenesis;
  • chemoprevention;
  • phytochemicals;
  • reactive oxygen species;
  • drug metabolism;
  • epigenetics;
  • muragenesis;
  • DNA repair;
  • antioxidant;
  • inflammation;
  • tumor promotion;
  • proliferation;
  • cell signalling;
  • cell differentiation

Summary

This chapter contains sections titled:

  • Cancer Chemoprevention

  • Molecular Mechanisms and Targets of Chemopreventive Agents

  • Perspectives

  • Conclusion

  • Acknowledgment

  • References