13. Trypanosomatid Protein Kinases as Potential Drug Targets

  1. Prof. Dr. Paul M. Selzer
  1. Martin Wiese1,
  2. Andrew Morris2 and
  3. Karen M. Grant3

Published Online: 28 JUL 2009

DOI: 10.1002/9783527626816.ch13

Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates

Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates

How to Cite

Wiese, M., Morris, A. and Grant, K. M. (2009) Trypanosomatid Protein Kinases as Potential Drug Targets, in Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates (ed P. M. Selzer), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527626816.ch13

Editor Information

  1. BioChemInformatics, Intervet Innovation GmbH, Zur Propstei, 55270 Schwabenheim, Germany

Author Information

  1. 1

    Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), John Arbuthnott Building, 27 Taylor Street, Glasgow, G4 0NR, UK

  2. 2

    Institute for Science and Technology in Medicine, Huxley Building, Keele University, Keele, Newcastle-under-Lyme, ST5 5BG, UK

  3. 3

    School of Health & Medicine, Division of Medicine, Faraday Building, Lancaster University, Lancaster, LA1 4YB, UK

Publication History

  1. Published Online: 28 JUL 2009
  2. Published Print: 22 APR 2009

ISBN Information

Print ISBN: 9783527323272

Online ISBN: 9783527626816

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Keywords:

  • protein-kinase inhibitors;
  • CMGC kinases;
  • trypanosomatid;
  • leishmania;
  • trypanosoma brucei;
  • trypanosoma cruzi;
  • drug targets

Summary

This chapter contains sections titled:

  • Introduction

  • Mitogen-Activated Protein Kinases

  • Cyclin-Dependent Kinases

  • Casein Kinase 1

  • Other Possible Protein Kinase Targets

  • Protein Kinase Inhibitors – Opportunities and Challenges

  • References