Chapter 12. Histone Methyltransferases as Novel Drug Targets

  1. Prof., Dr. Wolfgang Sippl1 and
  2. Prof., Dr. Manfred Jung2
  1. Prof., Dr. Manfred Jung

Published Online: 25 FEB 2010

DOI: 10.1002/9783527627073.ch12

Epigenetic Targets in Drug Discovery, Volume 42

Epigenetic Targets in Drug Discovery, Volume 42

How to Cite

Jung, M. (2009) Histone Methyltransferases as Novel Drug Targets, in Epigenetic Targets in Drug Discovery, Volume 42 (eds W. Sippl and M. Jung), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527627073.ch12

Editor Information

  1. 1

    Institut für Pharmazie, Martin-Luther-Universität, Wolfgang-Langenbeck-Straße 4, 06120 Halle, Germany

  2. 2

    Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität, Albertstraße 25, 79104 Freiburg, Germany

Author Information

  1. Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität, Albertstraße 25, 79104 Freiburg, Germany

Publication History

  1. Published Online: 25 FEB 2010
  2. Published Print: 24 JUN 2009

Book Series:

  1. Methods and Principles in Medicinal Chemistry

Book Series Editors:

  1. Prof., Dr. Raimund Mannhold3,
  2. Prof., Dr. Hugo Kubinyi4 and
  3. Prof., Dr. Gerd Folkers5

Series Editor Information

  1. 3

    Molecular Drug Research Group, Heinrich-Heine-Universität, Universitätsstraße 1, 40225 Düsseldorf, Germany

  2. 4

    Donnersbergstrasse 9, 67256 Weisenheim am Sand, Germany

  3. 5

    Collegium Helveticum, STW/ETH Zurich, 8092 Zurich, Switzerland

ISBN Information

Print ISBN: 9783527323555

Online ISBN: 9783527627073

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Keywords:

  • histone methyltransferases;
  • PRMT;
  • arginine methyltransferase;
  • lysine methyltransferase;
  • epigenetics

Summary

This chapter contains sections titled:

  • Introduction

  • Protein Methylation

  • Histone Demethylation

  • Histone Methyltransferases

  • Histone Methyltransferase Inhibitors

  • Concluding Remarks

  • References