Chapter 13. Histone Demethylases

  1. Prof., Dr. Wolfgang Sippl3 and
  2. Prof., Dr. Manfred Jung4
  1. Rasmus P. Clausen1,
  2. Marianne T. Pedersen2 and
  3. Kristian Helin2

Published Online: 25 FEB 2010

DOI: 10.1002/9783527627073.ch13

Epigenetic Targets in Drug Discovery, Volume 42

Epigenetic Targets in Drug Discovery, Volume 42

How to Cite

Clausen, R. P., Pedersen, M. T. and Helin, K. (2009) Histone Demethylases, in Epigenetic Targets in Drug Discovery, Volume 42 (eds W. Sippl and M. Jung), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527627073.ch13

Editor Information

  1. 3

    Institut für Pharmazie, Martin-Luther-Universität, Wolfgang-Langenbeck-Straße 4, 06120 Halle, Germany

  2. 4

    Institut für Pharmazeutische Wissenschaften, Albert-Ludwigs-Universität, Albertstraße 25, 79104 Freiburg, Germany

Author Information

  1. 1

    University of Copenhagen, Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, 2100 Copenhagen, Denmark

  2. 2

    University of Copenhagen, Biotech Research and Innovation Centre, (BRIC) and Centre for Epigenetics, 2200 Copenhagen, Denmark

  1. RPC and MTP contributed equally to this chapter.

Publication History

  1. Published Online: 25 FEB 2010
  2. Published Print: 24 JUN 2009

Book Series:

  1. Methods and Principles in Medicinal Chemistry

Book Series Editors:

  1. Prof., Dr. Raimund Mannhold5,
  2. Prof., Dr. Hugo Kubinyi6 and
  3. Prof., Dr. Gerd Folkers7

Series Editor Information

  1. 5

    Molecular Drug Research Group, Heinrich-Heine-Universität, Universitätsstraße 1, 40225 Düsseldorf, Germany

  2. 6

    Donnersbergstrasse 9, 67256 Weisenheim am Sand, Germany

  3. 7

    Collegium Helveticum, STW/ETH Zurich, 8092 Zurich, Switzerland

ISBN Information

Print ISBN: 9783527323555

Online ISBN: 9783527627073

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Keywords:

  • histone demethylases;
  • chromatin

Summary

This chapter contains sections titled:

  • Introduction

  • Chromatin

  • Histone Methylation and Demethylation

  • Histone Demethylases

  • LSD1/KDM1

  • JmjC Domain-Containing Demethylases

  • Summary

  • References