Chapter 28. Genetic Counseling for Hereditary Tumors

  1. Prof. Dr. Heike Allgayer PhD2,
  2. Prof. Dr. Helga Rehder3 and
  3. Prof. Dr. Simone Fulda4
  1. Dorothea Gadzicki and
  2. Brigitte Schlegelberger

Published Online: 21 AUG 2009

DOI: 10.1002/9783527627523.ch28

Hereditary Tumors: From Genes to Clinical Consequences

Hereditary Tumors: From Genes to Clinical Consequences

How to Cite

Gadzicki, D. and Schlegelberger, B. (2008) Genetic Counseling for Hereditary Tumors, in Hereditary Tumors: From Genes to Clinical Consequences (eds H. Allgayer, H. Rehder and S. Fulda), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527627523.ch28

Editor Information

  1. 2

    University of Heidelberg and DKFZ (German Cancer Research Center) Heidelberg, Medical Faculty Mannheim, Chair of Experimental Surgery, Theodor-Kutzer-Ufer 1–3, 68167 Mannheim, Germany

  2. 3

    Medical University Vienna, Department of Medical Genetics, Währinger Strasse 10, 1090 Wien, Austria

  3. 4

    Ulm University Children's Hospital, Eythstrasse 24, 89075 Ulm, Germany

Author Information

  1. Hannover Medical School, Institute of Cell and Molecular Pathology, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany

Publication History

  1. Published Online: 21 AUG 2009
  2. Published Print: 17 DEC 2008

ISBN Information

Print ISBN: 9783527320288

Online ISBN: 9783527627523



  • genetic counseling;
  • familial;
  • informed consent;
  • pedigree analysis;
  • risk assessment model;
  • sporadic


The goal of cancer genetic counseling is to educate counselees about their risk of developing cancer, help them to derive the personal significance from cancer genetic information, to empower them to make educated, informed decisions (“informed consent”) about genetic testing, cancer screening, and cancer prevention, and to support them in coping with the situation. Thus, genetic counseling is an integral part of the cancer risk assessment process and should be offered before and after genetic testing. In this chapter, different aspects of cancer genetic counseling, for example, documentation of the pedigree and the medical history of the family, tailored information giving, shared decision-making regarding genetic testing, risk assessment tools, interaction with other specialists, and transmission of the information within the family, are discussed.