Chapter 30. Molecular Targeted Therapy

  1. Prof. Dr. Heike Allgayer PhD1,
  2. Prof. Dr. Helga Rehder2 and
  3. Prof. Dr. Simone Fulda3
  1. Prof. Dr. Heike Allgayer PhD1 and
  2. Prof. Dr. Simone Fulda3

Published Online: 21 AUG 2009

DOI: 10.1002/9783527627523.ch30

Hereditary Tumors: From Genes to Clinical Consequences

Hereditary Tumors: From Genes to Clinical Consequences

How to Cite

Allgayer, H. and Fulda, S. (2008) Molecular Targeted Therapy, in Hereditary Tumors: From Genes to Clinical Consequences (eds H. Allgayer, H. Rehder and S. Fulda), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527627523.ch30

Editor Information

  1. 1

    University of Heidelberg and DKFZ (German Cancer Research Center) Heidelberg, Medical Faculty Mannheim, Chair of Experimental Surgery, Theodor-Kutzer-Ufer 1–3, 68167 Mannheim, Germany

  2. 2

    Medical University Vienna, Department of Medical Genetics, Währinger Strasse 10, 1090 Wien, Austria

  3. 3

    Ulm University Children's Hospital, Eythstrasse 24, 89075 Ulm, Germany

Author Information

  1. 1

    University of Heidelberg and DKFZ (German Cancer Research Center) Heidelberg, Medical Faculty Mannheim, Chair of Experimental Surgery, Theodor-Kutzer-Ufer 1–3, 68167 Mannheim, Germany

  2. 3

    Ulm University Children's Hospital, Eythstrasse 24, 89075 Ulm, Germany

Publication History

  1. Published Online: 21 AUG 2009
  2. Published Print: 17 DEC 2008

ISBN Information

Print ISBN: 9783527320288

Online ISBN: 9783527627523

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Keywords:

  • EGF-receptor;
  • growth factors;
  • molecular markers;
  • therapeutics

Summary

Progress in the elucidation of molecular targets in human cancers in the last decades has provided the basis for the development of novel therapeutics. A huge variety of potential target structures have been identified, many of which are already exploited for therapeutic purposes. To conclude this book on hereditary tumors, with an outlook on general diagnostic and therapeutic challenges and chances, this review introduces the reader into the concept of molecular targeted therapies, and provides some prototypic examples.