Chapter 11. Oxalate and Primary Hyperoxaluria

  1. Prof. Peter J. O'Brien2 and
  2. Prof. W. Robert Bruce3,4
  1. Christopher J. Danpure

Published Online: 25 JAN 2010

DOI: 10.1002/9783527628100.ch11

Endogenous Toxins: Targets for Disease Treatment and Prevention

Endogenous Toxins: Targets for Disease Treatment and Prevention

How to Cite

Danpure, C. J. (2010) Oxalate and Primary Hyperoxaluria, in Endogenous Toxins: Targets for Disease Treatment and Prevention (eds P. J. O'Brien and W. R. Bruce), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527628100.ch11

Editor Information

  1. 2

    University of Toronto, Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy, Room 1004, College Street 144, Toronto, ON M5S 3M2, Canada

  2. 3

    University of Toronto, Fitz Gerald Building, Room 342, College Street 150, Toronto, ON M5S 3E2, Canada

  3. 4

    University of Toronto, Department of Nutritional Sciences, Faculty of Medicine, Toronto, Ontario M5S 2E3, Canada

Author Information

  1. University College London, Department of Cell and Developmental Biology, Division of Biosciences, Gower Street, London WC1E 6BT, UK

Publication History

  1. Published Online: 25 JAN 2010
  2. Published Print: 21 OCT 2009

ISBN Information

Print ISBN: 9783527323630

Online ISBN: 9783527628100



  • primary hyperoxaluria;
  • calcium oxalate;
  • hyperglycolic aciduria;
  • urolithiasis;
  • nephrolithiasis;
  • nephrocalcinosis;
  • alanine;
  • glyoxylate reductase;
  • kidney stones;
  • oxalate


This chapter contains sections titled:

  • Oxalate as an Endogenous Toxin

  • Hereditary Oxalate Overproduction – The Primary Hyperoxalurias

  • Cytotoxicity of Oxalate, Calcium Oxalate, and Related Metabolites

  • Conclusions

  • References