Chapter 16. Genetic Defects in Iron and Copper Trafficking

  1. Prof. Peter J. O'Brien2 and
  2. Prof. W. Robert Bruce3,4
  1. Douglas M. Templeton

Published Online: 25 JAN 2010

DOI: 10.1002/9783527628100.ch16

Endogenous Toxins: Targets for Disease Treatment and Prevention

Endogenous Toxins: Targets for Disease Treatment and Prevention

How to Cite

Templeton, D. M. (2009) Genetic Defects in Iron and Copper Trafficking, in Endogenous Toxins: Targets for Disease Treatment and Prevention (eds P. J. O'Brien and W. R. Bruce), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527628100.ch16

Editor Information

  1. 2

    University of Toronto, Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy, Room 1004, College Street 144, Toronto, ON M5S 3M2, Canada

  2. 3

    University of Toronto, Fitz Gerald Building, Room 342, College Street 150, Toronto, ON M5S 3E2, Canada

  3. 4

    University of Toronto, Department of Nutritional Sciences, Faculty of Medicine, Toronto, Ontario M5S 2E3, Canada

Author Information

  1. University of Toronto, Department of Laboratory, Medicine and Pathobiology, 1 King's College Circle, Toronto, ON M5S 1A8, Canada

Publication History

  1. Published Online: 25 JAN 2010
  2. Published Print: 21 OCT 2009

ISBN Information

Print ISBN: 9783527323630

Online ISBN: 9783527628100

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Keywords:

  • reactive oxygen species (ROS);
  • hemochromatosis;
  • liver disease;
  • ATP7A/ATP7B;
  • Wilson disease;
  • Menkes disease;
  • siderosis;
  • mitochondria;
  • iron overload

Summary

This chapter contains sections titled:

  • Introduction and Terminology

  • Iron

  • Copper

  • Summary

  • References