Chapter 2. Modification of Cysteine Residues in Protein by Endogenous Oxidants and Electrophiles

  1. Prof. Peter J. O'Brien2 and
  2. Prof. W. Robert Bruce3,4
  1. Norma Frizzell and
  2. John W. Baynes

Published Online: 25 JAN 2010

DOI: 10.1002/9783527628100.ch2

Endogenous Toxins: Targets for Disease Treatment and Prevention

Endogenous Toxins: Targets for Disease Treatment and Prevention

How to Cite

Frizzell, N. and Baynes, J. W. (2010) Modification of Cysteine Residues in Protein by Endogenous Oxidants and Electrophiles, in Endogenous Toxins: Targets for Disease Treatment and Prevention (eds P. J. O'Brien and W. R. Bruce), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527628100.ch2

Editor Information

  1. 2

    University of Toronto, Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy, Room 1004, College Street 144, Toronto, ON M5S 3M2, Canada

  2. 3

    University of Toronto, Fitz Gerald Building, Room 342, College Street 150, Toronto, ON M5S 3E2, Canada

  3. 4

    University of Toronto, Department of Nutritional Sciences, Faculty of Medicine, Toronto, Ontario M5S 2E3, Canada

Author Information

  1. University of South Carolina, Department of Exercise Science, Public Health Research Center, 927 Assembly St., Columbia, SC 29208, USA

Publication History

  1. Published Online: 25 JAN 2010
  2. Published Print: 21 OCT 2009

ISBN Information

Print ISBN: 9783527323630

Online ISBN: 9783527628100

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Keywords:

  • succination;
  • glutathionylation;
  • glyceraldehyde-3-phosphate dehydrogenase;
  • Maillard reaction;
  • transglycosylation;
  • carboxyalkylation

Summary

This chapter contains sections titled:

  • Introduction

  • Autoxidation of Cysteine

  • Glutathione

  • Lipoxidation

  • Maillard Reactions of Cysteine

  • Succination

  • Conclusion

  • Acknowledgment

  • References