Chapter 32. Endogenous Toxins Associated with Life Expectancy and Aging
- Prof. Peter J. O'Brien2,
- Prof. W. Robert Bruce3,4
Published Online: 25 JAN 2010
DOI: 10.1002/9783527628100.ch32
Copyright © 2010 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Endogenous Toxins: Targets for Disease Treatment and Prevention
Additional Information
How to Cite
Ayala, V., Boada, J., Serrano, J., Portero-Otín, M. and Pamplona, R. (2010) Endogenous Toxins Associated with Life Expectancy and Aging, in Endogenous Toxins: Targets for Disease Treatment and Prevention (eds P. J. O'Brien and W. R. Bruce), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527628100.ch32
Editor Information
- 2
University of Toronto, Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy, Room 1004, College Street 144, Toronto, ON M5S 3M2, Canada
- 3
University of Toronto, Fitz Gerald Building, Room 342, College Street 150, Toronto, ON M5S 3E2, Canada
- 4
University of Toronto, Department of Nutritional Sciences, Faculty of Medicine, Toronto, Ontario M5S 2E3, Canada
Publication History
- Published Online: 25 JAN 2010
- Published Print: 21 OCT 2009
ISBN Information
Print ISBN: 9783527323630
Online ISBN: 9783527628100
- Summary
- Chapter
- References
Keywords:
- aging;
- caloric, methionine and protein restriction;
- DNA damage;
- free radicals;
- evolution;
- life span;
- membrane unsaturation;
- methionine;
- mitochondria;
- protein oxidation;
- reactive oxygen species production
Summary
This chapter contains sections titled:
Introduction
Metabolism(s)
The Rate of Generation of Damage Induced by Mitochondrial Free Radicals and Life Span
Structural Components that are Highly Resistant to Oxidative Stress and Life Span
Oxidative Stress, Aging, and Dietary Restriction
Nutritional Considerations on Methionine: A Public Health Matter
Acknowledgments
References