Chapter 35. Genotoxicity of Endogenous Estrogens

  1. Prof. Peter J. O'Brien2 and
  2. Prof. W. Robert Bruce3,4
  1. James S. Wright

Published Online: 25 JAN 2010

DOI: 10.1002/9783527628100.ch35

Endogenous Toxins: Targets for Disease Treatment and Prevention

Endogenous Toxins: Targets for Disease Treatment and Prevention

How to Cite

Wright, J. S. (2009) Genotoxicity of Endogenous Estrogens, in Endogenous Toxins: Targets for Disease Treatment and Prevention (eds P. J. O'Brien and W. R. Bruce), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527628100.ch35

Editor Information

  1. 2

    University of Toronto, Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy, Room 1004, College Street 144, Toronto, ON M5S 3M2, Canada

  2. 3

    University of Toronto, Fitz Gerald Building, Room 342, College Street 150, Toronto, ON M5S 3E2, Canada

  3. 4

    University of Toronto, Department of Nutritional Sciences, Faculty of Medicine, Toronto, Ontario M5S 2E3, Canada

Author Information

  1. Carleton University, Department of Chemistry, 1125 Colonel By Drive, Ottawam, Ontario K1S 5B6, Canada

Publication History

  1. Published Online: 25 JAN 2010
  2. Published Print: 21 OCT 2009

ISBN Information

Print ISBN: 9783527323630

Online ISBN: 9783527628100

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Keywords:

  • estrogen;
  • estrogen genotoxicity;
  • quinone formation;
  • P450;
  • COMT;
  • NQO;
  • GSH

Summary

This chapter contains sections titled:

  • Introduction

  • Estrogens and Women's Health

  • Causes of Estrogen Genotoxicity

  • Enzymatic Reactions that Affect Estrogen Genotoxicity

  • Conclusions

  • Acknowledgment

  • References