Chapter 15. The Cholinergic Model for PTSD: From Acute Stress to PTSD, from Neuron to Network and Behavior

  1. Prof. Dr. Hermona Soreq2,
  2. Prof. Dr. Alon Friedman3 and
  3. Prof. Dr. Daniela Kaufer4
  1. Alon Friedman3 and
  2. Lev Pavlovsky1

Published Online: 2 DEC 2009

DOI: 10.1002/9783527628346.ch15

Stress - From Molecules to Behavior: A Comprehensive Analysis of the Neurobiology of Stress Responses

Stress - From Molecules to Behavior: A Comprehensive Analysis of the Neurobiology of Stress Responses

How to Cite

Friedman, A. and Pavlovsky, L. (2009) The Cholinergic Model for PTSD: From Acute Stress to PTSD, from Neuron to Network and Behavior, in Stress - From Molecules to Behavior: A Comprehensive Analysis of the Neurobiology of Stress Responses (eds H. Soreq, A. Friedman and D. Kaufer), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527628346.ch15

Editor Information

  1. 2

    The Hebrew University of Jerusalem, Department of Biological Chemistry, Safra Campus - Givat Ram, Jerusalem 91904, Israel

  2. 3

    Ben Gurion University of the Negev, Departments of Physiology and Neurosurgery, Zlotowksi Centre for Neuroscience, Beer Sheva 84105, Israel

  3. 4

    University of California, Berkeley, Department of Integrative Biology, 3060 Valley Life Sciences Bldg. 3140, Berkeley, CA 94720-3140, USA

Author Information

  1. 1

    Beilinson Campus, Department of Dermatology, Rabin Medical Center, Petah Tikva 49414, Israel

  2. 3

    Ben Gurion University of the Negev, Departments of Physiology and Neurosurgery, Zlotowksi Centre for Neuroscience, Beer Sheva 84105, Israel

Publication History

  1. Published Online: 2 DEC 2009
  2. Published Print: 11 NOV 2009

ISBN Information

Print ISBN: 9783527323746

Online ISBN: 9783527628346

SEARCH

Keywords:

  • acetylcholinesterase;
  • muscarine;
  • electrophysiology;
  • stress;
  • post-traumatic stress disorder

Summary

This chapter contains sections titled:

  • From Acute Stress to PTSD

  • Stress and Brain Cholinergic Pathways

  • Anatomical Considerations

  • Neurophysiological Considerations

  • Stress Induces Cholinergic Dysfunction

  • The Cholinergic Basis for PTSD: the Model

  • Summary

  • References