Chapter 19. Environmental Stress is Not Always Vicious: A Lesson from Heat Acclimation-Mediated Neuroprotection after Traumatic Brain Injury

  1. Prof. Dr. Hermona Soreq3,
  2. Prof. Dr. Alon Friedman4 and
  3. Prof. Dr. Daniela Kaufer5
  1. Michal Horowitz1 and
  2. Esther Shohami2

Published Online: 2 DEC 2009

DOI: 10.1002/9783527628346.ch19

Stress - From Molecules to Behavior: A Comprehensive Analysis of the Neurobiology of Stress Responses

Stress - From Molecules to Behavior: A Comprehensive Analysis of the Neurobiology of Stress Responses

How to Cite

Horowitz, M. and Shohami, E. (2009) Environmental Stress is Not Always Vicious: A Lesson from Heat Acclimation-Mediated Neuroprotection after Traumatic Brain Injury, in Stress - From Molecules to Behavior: A Comprehensive Analysis of the Neurobiology of Stress Responses (eds H. Soreq, A. Friedman and D. Kaufer), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527628346.ch19

Editor Information

  1. 3

    The Hebrew University of Jerusalem, Department of Biological Chemistry, Safra Campus - Givat Ram, Jerusalem 91904, Israel

  2. 4

    Ben Gurion University of the Negev, Departments of Physiology and Neurosurgery, Zlotowksi Centre for Neuroscience, Beer Sheva 84105, Israel

  3. 5

    University of California, Berkeley, Department of Integrative Biology, 3060 Valley Life Sciences Bldg. 3140, Berkeley, CA 94720-3140, USA

Author Information

  1. 1

    The Hebrew University of Jerusalem, Faculty of Dental Medicine, Laboratory of Environmental, Physiology, Jerusalem 91120, Israel

  2. 2

    The Hebrew University of Jerusalem, Department of Pharmacology, School of Pharmacy, Jerusalem 91120, Israel

Publication History

  1. Published Online: 2 DEC 2009
  2. Published Print: 11 NOV 2009

ISBN Information

Print ISBN: 9783527323746

Online ISBN: 9783527628346

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Keywords:

  • traumatic brain injury;
  • heat acclimation;
  • cross-tolerance;
  • precondition;
  • oxidative stress;
  • neuroinflammation;
  • erythropoietin

Summary

This chapter contains sections titled:

  • Introduction

  • TBI Damage – Detrimental Signaling and Possible Protective Pathways

  • Preconditioning: Inherent Protective Mechanisms Are Induced by Preceding Sub-Lethal (Multiple) Stressors

  • Heat Acclimation and Neuroprotection

  • Summary

  • References