Chapter 3.5. Fabrication and Application of Surface-Tethered Vesicles

  1. Dr. Renate Förch2,
  2. Prof. Dr. Holger Schönherr3 and
  3. Dr. A. Tobias A. Jenkins4
  1. Thomas Lloyd Williams1 and
  2. Dr. A. Tobias A. Jenkins4

Published Online: 9 SEP 2009

DOI: 10.1002/9783527628599.ch13

Surface Design: Applications in Bioscience and Nanotechnology

Surface Design: Applications in Bioscience and Nanotechnology

How to Cite

Williams, T. L. and Jenkins, A. T. A. (2009) Fabrication and Application of Surface-Tethered Vesicles, in Surface Design: Applications in Bioscience and Nanotechnology (eds R. Förch, H. Schönherr and A. T. A. Jenkins), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527628599.ch13

Editor Information

  1. 2

    Max-Planck-Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany

  2. 3

    University of Siegen, Department of Physical Chemistry, Adolf-Reichwein-Straße 2, 57076 Siegen, Germany

  3. 4

    University of Bath, Department of Chemistry, Bath BA2 7AY, United Kingdom

Author Information

  1. 1

    University of Sussex, School of Life Sciences, Department of Biochemistry, Brighton, BN1 9QG, United Kingdom

  2. 4

    University of Bath, Department of Chemistry, Bath BA2 7AY, United Kingdom

Publication History

  1. Published Online: 9 SEP 2009
  2. Published Print: 12 JUN 2009

ISBN Information

Print ISBN: 9783527407897

Online ISBN: 9783527628599

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Keywords:

  • surface-tethered vesicles;
  • fabrication;
  • application;
  • lipid vesicles;
  • polymer-tethered LUVs;
  • sam- tethered LUVs;
  • streptavidin-tethered LUVs;
  • solid-supported lbvs

Summary

This chapter briefly reviews background on the use of lipid bilayer vesicles (LBVs) as cell-membrane models and details the surface-immobilization strategies of such vesicles. It then proceeds to describe recent measurements of supported vesicles, with a study of membrane permeability, and studies of the interaction of membrane permeabilizing proteins with such solid-supported LBVs.