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Chemistry and Applications of Iron–TAML Catalysts in Green Oxidation Processes Based on Hydrogen Peroxide

Part 1. Homogeneous Catalysis

  1. Terrence J. Collins,
  2. Sushil K. Khetan,
  3. Alexander D. Ryabov

Published Online: 15 JUL 2010

DOI: 10.1002/9783527628698.hgc003

Handbook of Green Chemistry

Handbook of Green Chemistry

How to Cite

Collins, T. J., Khetan, S. K. and Ryabov, A. D. 2010. Chemistry and Applications of Iron–TAML Catalysts in Green Oxidation Processes Based on Hydrogen Peroxide. Handbook of Green Chemistry. 1:3:39–77.

Author Information

  1. Carnegie Mellon University, Institute for Green Science, Pittsburgh, PA, USA

Publication History

  1. Published Online: 15 JUL 2010

Abstract

Iron–tetraamido macrocyclic ligand (TAML) activators have been designed and developed to provide small-molecule mimics, the peroxidase enzymes. Fe–TAML activators are proving to be highly active catalysts that function effectively at very low concentrations from nanomolar to low micromolar. Notably, they are capable of performing many thousands of turnovers per minute under ambient conditions, of functioning over a broad pH range from acidic and most notably for iron catalyst to basic and even to highly basic, of presenting a broad range of selectivities and oxidative aggression determined by the conditions of use and the choice of catalyst over the 14 catalysts presented. The catalysts have fulfilled the design criteria and now provide the basis of platform technology for myriad applications. Published kinetics and mechanistic interpretations are reviewed to illustrate the success of the design protocol. Published applications are briefly described. A highly developed field of use involves the use of Fe–TAML–peroxide for the purification of water of persistent pollutants and hardy pathogens.

Keywords:

  • iron–TAML activators;
  • oxidation;
  • homogeneous catalysis;
  • water purification;
  • hydrogen peroxide;
  • green chemistry