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Biocatalytic Hydrolysis of Nitriles

Part 3. Biocatalysis

  1. Dean Brady

Published Online: 15 JUL 2010

DOI: 10.1002/9783527628698.hgc026

Handbook of Green Chemistry

Handbook of Green Chemistry

How to Cite

Brady, D. 2010. Biocatalytic Hydrolysis of Nitriles. Handbook of Green Chemistry. 3:2:27–49.

Author Information

  1. CSIR Biosciences, Modderfontein, South Africa

Publication History

  1. Published Online: 15 JUL 2010

Chemistry Terms

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The function, uses and commercial applications of nitrile biocatalysts are reviewed. Particular consideration is given to benefits of the technology regarding the impact of nitrile hydrolysis on the environment. The challenges, solutions and opportunities facing the broader application of this technology are also discussed.


  • nitriles;
  • amides;
  • carboxylic acids;
  • biocatalysis;
  • hydrolysis;
  • nitrilase;
  • nitrile hydratase;
  • amidase