Chapter 19. Regulation of Carbohydrate Utilization by Phosphotransferase System-Mediated Protein Phosphorylation

  1. Prof. Dr. Reinhard Krämer3 and
  2. Prof. Dr. Kirsten Jung4
  1. Boris Görke1 and
  2. Birte Reichenbach2

Published Online: 29 MAR 2010

DOI: 10.1002/9783527629237.ch19

Bacterial Signaling

Bacterial Signaling

How to Cite

Görke, B. and Reichenbach, B. (2009) Regulation of Carbohydrate Utilization by Phosphotransferase System-Mediated Protein Phosphorylation, in Bacterial Signaling (eds R. Krämer and K. Jung), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527629237.ch19

Editor Information

  1. 3

    University of Cologne, Insitute of Biochemistry, Zülpicher Strasse 47, 50674 Cologne, Germany

  2. 4

    Ludwig-Maximilians-Universität München, Department of Biology – Microbiology, Grosshaderner Strasse 2–4, 82152 Planegg-Martinsried, Germany

Author Information

  1. 1

    Universität Göttingen, Institut für Mikrobiologie und Genetik, Abteilung für Allgemeine Mikrobiologie, Grisebachstrasse 8, 37077 Göttingen, Germany

  2. 2

    Georg-August-University Göttingen, Department of General Microbiology, Grisebachstrasse 8, 37077 Göttingen, Germany

Publication History

  1. Published Online: 29 MAR 2010
  2. Published Print: 16 DEC 2009

ISBN Information

Print ISBN: 9783527323654

Online ISBN: 9783527629237



  • carbohydrate utilization;
  • phosphotransferase system;
  • protein phosphorylation;
  • catabolite;
  • chemotaxis


This chapter contains sections titled:

  • Introduction

  • Unique Features of the Bacterial PTS

  • Phosphorylation of the IIAGlc Subunit of the Glucose Transporter Triggers Global CCR in Enteric Bacteria

  • A Second Key Mechanism of CCR: Phosphorylation of IIAGlc Controls Inducer Exclusion in Enteric Bacteria

  • Phosphorylation of Ser46 of HPr Triggers CCR in Low-GC Gram-Positive Bacteria

  • Phosphorylation of HPr by the Bifunctional Kinase/Phosphorylase Links CCR to the Metabolic State of the Cell in Gram-Positive Bacteria

  • HPr Controls Inducer Exclusion in Low-GC Gram-Positive Bacteria

  • Control of Transcription Regulators by EII

  • Catabolite Control of PRD-Containing Regulators by HPr(His∼P)-Mediated Phosphorylation

  • PTS-Dependent Regulation of Chemotaxis

  • Regulatory Functions of Paralogous PTSs

  • References