Chapter 20. cAMP Signaling in Prokaryotes

  1. Prof. Dr. Reinhard Krämer2 and
  2. Prof. Dr. Kirsten Jung3
  1. Knut Jahreis

Published Online: 29 MAR 2010

DOI: 10.1002/9783527629237.ch20

Bacterial Signaling

Bacterial Signaling

How to Cite

Jahreis, K. (2009) cAMP Signaling in Prokaryotes, in Bacterial Signaling (eds R. Krämer and K. Jung), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527629237.ch20

Editor Information

  1. 2

    University of Cologne, Insitute of Biochemistry, Zülpicher Strasse 47, 50674 Cologne, Germany

  2. 3

    Ludwig-Maximilians-Universität München, Department of Biology – Microbiology, Grosshaderner Strasse 2–4, 82152 Planegg-Martinsried, Germany

Author Information

  1. Universität Osnabrück, Fachbereich Biologie/Chemie, AG Genetik, Barbarastrasse 11, 49069 Osnabrück, Germany

Publication History

  1. Published Online: 29 MAR 2010
  2. Published Print: 16 DEC 2009

ISBN Information

Print ISBN: 9783527323654

Online ISBN: 9783527629237



  • cAMP;
  • signaling;
  • prokaryote;
  • carbon catabolite repression;
  • cAMP receptor protein;
  • phosphotransferase system


This chapter contains sections titled:

  • Introduction

  • CCR – A Short Historical Account

  • Regulation of Intracellular cAMP Levels: PTS as a Sensor and Signal Transduction System that Modulates AC Activity

  • Another Extension of the Simple Model: Catabolite Repression by Non-PTS Substrates: The PEP: Pyruvate Ratio is a Key Node in Carbon and Energy Metabolism

  • cAMP Excretion and Phosphodiesterase Activity

  • Function of the cAMP–CRP Complex

  • cAMP–CRP Modulon and the CFU “Carbohydrate Catabolism/Quest for Food”

  • Interactions with Other Regulatory Systems

  • Mathematical and Computer-Assisted Modeling of Catabolite Repression

  • Conclusions

  • References