Chapter 24. Signal Transduction by Serine/Threonine Protein Kinases in Bacteria

  1. Prof. Dr. Reinhard Krämer2 and
  2. Prof. Dr. Kirsten Jung3
  1. Michael Bott

Published Online: 29 MAR 2010

DOI: 10.1002/9783527629237.ch24

Bacterial Signaling

Bacterial Signaling

How to Cite

Bott, M. (2009) Signal Transduction by Serine/Threonine Protein Kinases in Bacteria, in Bacterial Signaling (eds R. Krämer and K. Jung), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527629237.ch24

Editor Information

  1. 2

    University of Cologne, Insitute of Biochemistry, Zülpicher Strasse 47, 50674 Cologne, Germany

  2. 3

    Ludwig-Maximilians-Universität München, Department of Biology – Microbiology, Grosshaderner Strasse 2–4, 82152 Planegg-Martinsried, Germany

Author Information

  1. Forschungszentrum Jülich, Institut für Biotechnologie, 52425 Jülich, Germany

Publication History

  1. Published Online: 29 MAR 2010
  2. Published Print: 16 DEC 2009

ISBN Information

Print ISBN: 9783527323654

Online ISBN: 9783527629237



  • signal transduction;
  • serine/threonine protein kinase;
  • phosphorylation;
  • gene expression;
  • enzyme activity


This chapter contains sections titled:

  • Introduction

  • Discovery and Distribution of STPKs in Prokaryotes

  • Serine/Threonine Phosphorylation versus Histidine/Aspartate Phosphorylation

  • Domain Architecture of STPKs

  • Structural Studies on STPKs

  • Signal Transduction by STPKs

  • Control of Gene Expression by PknB via the Activity of Sigma Factors

  • Control of Gene Expression by PknH via the Transcriptional Regulator EmbR

  • Direct Control of Enzyme Activities by STPKs

  • Indirect Control of Enzyme Activity by PknG and its Target Protein OdhI/GarA

  • Conclusions and Outlook

  • References