Chapter 10. Leptin Secretion and Action

  1. Todd Leff2 and
  2. James G. Granneman3
  1. Robert V. Considine

Published Online: 16 APR 2010

DOI: 10.1002/9783527629527.ch10

Adipose Tissue in Health and Disease

Adipose Tissue in Health and Disease

How to Cite

Considine, R. V. (2010) Leptin Secretion and Action, in Adipose Tissue in Health and Disease (eds T. Leff and J. G. Granneman), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527629527.ch10

Editor Information

  1. 2

    Wayne State University School of Medicine, Department of Pathology, 540 E. Canfield, Detroit, MI 48201, USA

  2. 3

    Wayne State University School of Medicine, Center for Integrative Metabolic and Endocrine Research, Department of Psychiatry, 550 E. Canfield, Detroit, MI 48201, USA

Author Information

  1. Indiana University School of Medicine, Division of Endocrinology, 541 N. Clinical Drive, Indianapolis, IN 46202, USA

Publication History

  1. Published Online: 16 APR 2010
  2. Published Print: 10 MAR 2010

ISBN Information

Print ISBN: 9783527318575

Online ISBN: 9783527629527

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Keywords:

  • leptin;
  • transcriptional regulation;
  • obesity;
  • hyperleptinemia;
  • hypertension

Summary

This chapter contains sections titled:

  • Introduction

  • Leptin Synthesis

  • Leptin Receptors

  • Leptin Action in the Central Nervous System

  • Leptin Resistance in Obesity

  • Metabolic Complications of Hyperleptinemia in Obesity

  • Leptin Therapy in Humans

  • Conclusions

  • References