Chapter 23. Peroxisome Proliferator-Activated Receptor-γ: A Key Regulator of Adipose Tissue Formation, Remodeling, and Metabolism

  1. Todd Leff2 and
  2. James G. Granneman3
  1. Olga Astapova1 and
  2. Todd Leff2

Published Online: 16 APR 2010

DOI: 10.1002/9783527629527.ch23

Adipose Tissue in Health and Disease

Adipose Tissue in Health and Disease

How to Cite

Astapova, O. and Leff, T. (2010) Peroxisome Proliferator-Activated Receptor-γ: A Key Regulator of Adipose Tissue Formation, Remodeling, and Metabolism, in Adipose Tissue in Health and Disease (eds T. Leff and J. G. Granneman), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527629527.ch23

Editor Information

  1. 2

    Wayne State University School of Medicine, Department of Pathology, 540 E. Canfield, Detroit, MI 48201, USA

  2. 3

    Wayne State University School of Medicine, Center for Integrative Metabolic and Endocrine Research, Department of Psychiatry, 550 E. Canfield, Detroit, MI 48201, USA

Author Information

  1. 1

    Wayne State University School of Medicine, Department of Pathology, 540 E. Canfield, Detroit, MI 48201, USA

  2. 2

    Wayne State University School of Medicine, Department of Pathology, 540 E. Canfield, Detroit, MI 48201, USA

Publication History

  1. Published Online: 16 APR 2010
  2. Published Print: 10 MAR 2010

ISBN Information

Print ISBN: 9783527318575

Online ISBN: 9783527629527

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Keywords:

  • transcription factor;
  • peroxisome proliferator-activated receptor-γ;
  • adipose tissue;
  • adipogenesis;
  • white fat;
  • brown fat

Summary

This chapter contains sections titled:

  • Introduction

  • Molecular Biology of PPAR-γ

  • PPAR-γ is a Master Regulator of Adipose Tissue Development

  • Metabolic Functions of PPAR-γ

  • White versus Brown Fat-Specific Functions of PPAR-γ

  • PPAR-γ Function in Adipose Tissue Maintenance and Remodeling

  • Conclusions

  • References