Chapter 6. New Developments in the Lipolytic Processing of Triglyceride-Rich Lipoproteins

  1. Todd Leff4 and
  2. James G. Granneman5
  1. André Bensadoun1,
  2. Anne P. Beigneux2,
  3. Loren G. Fong3 and
  4. Stephen G. Young2

Published Online: 16 APR 2010

DOI: 10.1002/9783527629527.ch6

Adipose Tissue in Health and Disease

Adipose Tissue in Health and Disease

How to Cite

Bensadoun, A., Beigneux, A. P., Fong, L. G. and Young, S. G. (2010) New Developments in the Lipolytic Processing of Triglyceride-Rich Lipoproteins, in Adipose Tissue in Health and Disease (eds T. Leff and J. G. Granneman), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527629527.ch6

Editor Information

  1. 4

    Wayne State University School of Medicine, Department of Pathology, 540 E. Canfield, Detroit, MI 48201, USA

  2. 5

    Wayne State University School of Medicine, Center for Integrative Metabolic and Endocrine Research, Department of Psychiatry, 550 E. Canfield, Detroit, MI 48201, USA

Author Information

  1. 1

    Cornell University, Division of Nutritional Sciences, 321 Savage Hall, Ithaca, NY 14853, USA

  2. 2

    University of California, David Geffen School of Medicine, Department of Medicine, Division of Cardiology, 650 Charles E. Young Drive South, A2-237 CHS Bldg., Los Angeles, CA 90095, USA

  3. 3

    University of California, David Geffen School of Medicine, Department of Medicine, Division of Cardiology, 695 Charles E. Young Drive South, Gonda Bldg., Rm4524, Los Angeles, CA 90095, USA

Publication History

  1. Published Online: 16 APR 2010
  2. Published Print: 10 MAR 2010

ISBN Information

Print ISBN: 9783527318575

Online ISBN: 9783527629527

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Keywords:

  • lipolytic processing;
  • triglyceride;
  • lipoproteins;
  • angiopoietin;
  • lipolysis;
  • lipoprotein lipase;
  • Apo-AV;
  • angiopoietin-like protein 4 (ANGPTL4);
  • glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 (GPIHBP1)

Summary

This chapter contains sections titled:

  • Introduction

  • LPL

  • Functional Domains of LPL

  • Regulation of LPL Activity by Angiopoietin-Like Proteins

  • Role of GPIHBP1 in the Lipolysis of Triglyceride-Rich Lipoproteins

  • Role of Apo-AV in Lipolysis

  • Newly Discovered Regulators of LPL Activity and their Physiological Significance

  • References