Chapter 9. Signaling Pathways Controlling Lipolysis and Lipid Mobilization in Humans

  1. Todd Leff2 and
  2. James G. Granneman3
  1. Max Lafontan

Published Online: 16 APR 2010

DOI: 10.1002/9783527629527.ch9

Adipose Tissue in Health and Disease

Adipose Tissue in Health and Disease

How to Cite

Lafontan, M. (2010) Signaling Pathways Controlling Lipolysis and Lipid Mobilization in Humans, in Adipose Tissue in Health and Disease (eds T. Leff and J. G. Granneman), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527629527.ch9

Editor Information

  1. 2

    Wayne State University School of Medicine, Department of Pathology, 540 E. Canfield, Detroit, MI 48201, USA

  2. 3

    Wayne State University School of Medicine, Center for Integrative Metabolic and Endocrine Research, Department of Psychiatry, 550 E. Canfield, Detroit, MI 48201, USA

Author Information

  1. Institut de Médecine Moléculaire de Rangueil, INSERM Unit 858, BP 84225, 31432 Toulouse Cedex 4, France

Publication History

  1. Published Online: 16 APR 2010
  2. Published Print: 10 MAR 2010

ISBN Information

Print ISBN: 9783527318575

Online ISBN: 9783527629527

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Keywords:

  • signaling pathways;
  • lipolysis;
  • lipid mobilization;
  • triacylglycerol;
  • insulin;
  • natriuretic peptide;
  • catecholamines;
  • adrenergic receptors

Summary

This chapter contains sections titled:

  • Introduction

  • Role of Lipases in the Regulation of Hydrolysis of Fat Cell Triacylglycerols

  • Adrenergic Control of cAMP Production, Lipolysis and Lipid Mobilization

  • Control of cAMP Production by Adenylyl Cyclase Inhibitors – Inhibition of Lipolysis

  • Insulin: A Major Antilipolytic Agent Controlling cAMP Degradation

  • Natriuretic Peptides Control cGMP Production, Lipolysis, and Lipid Mobilization in Humans

  • Other Lipolytic Pathways

  • Future Trends and Pharmacological Prospects

  • References