Chapter 17. Lymphangioleiomyomatosis and Pulmonary Disease in TSC

  1. Dr. David J. Kwiatkowski3,
  2. Dr. Vicky Holets Whittemore4 and
  3. Dr. Elizabeth A. Thiele5
  1. Francis X. McCormack1 and
  2. Elizabeth P. Henske2

Published Online: 9 JUN 2010

DOI: 10.1002/9783527630073.ch17

Tuberous Sclerosis Complex: Genes, Clinical Features and Therapeutics

Tuberous Sclerosis Complex: Genes, Clinical Features and Therapeutics

How to Cite

McCormack, F. X. and Henske, E. P. (2010) Lymphangioleiomyomatosis and Pulmonary Disease in TSC, in Tuberous Sclerosis Complex: Genes, Clinical Features and Therapeutics (eds D. J. Kwiatkowski, V. H. Whittemore and E. A. Thiele), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527630073.ch17

Editor Information

  1. 3

    Brigham & Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, 1 Blackfan Circle, Boston, MA 02115, USA

  2. 4

    Tuberous Sclerosis Alliance, 801 Roeder Road, Silver Spring, MD 20910, USA

  3. 5

    Carol & James Herscot Center For TCS, Massachusetts General Hospital, Department of Neurology, 175 Cambridge Street, Boston, MA 02114, USA

Author Information

  1. 1

    The University of Cincinnati, Division of Pulmonary, Critical Care and Sleep Medicine, Cincinnati, OH 45219, USA

  2. 2

    Harvard Medical School, Brigham and Women's Hospital, Center for LAM Research and Patient Care, Boston, MA 02115, USA

Publication History

  1. Published Online: 9 JUN 2010
  2. Published Print: 21 APR 2010

ISBN Information

Print ISBN: 9783527322015

Online ISBN: 9783527630073

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Keywords:

  • lymphangioleiomyomatosis;
  • multinodular multifocal pneumocyte hyperplasia;
  • pleurodesis;
  • sporadic lymphangioleiomyomatosis;
  • tuberous sclerosis complex;
  • vascular endothelial growth factor D

Summary

This chapter contains sections titled:

  • Introduction

  • Historical Features of LAM

  • Epidemiology

  • Clinical Presentation

  • Diagnosis

  • Pathology and Laboratory Studies

  • Physiology

  • Radiology

  • Clinical Course and Management

  • Genetic Basis and Molecular Pathology

  • Challenges and Future Directions

  • References