Chapter 7. Rat and Mouse Models of Tuberous Sclerosis

  1. Dr. David J. Kwiatkowski1,
  2. Dr. Vicky Holets Whittemore2 and
  3. Dr. Elizabeth A. Thiele3
  1. Dr. David J. Kwiatkowski

Published Online: 9 JUN 2010

DOI: 10.1002/9783527630073.ch7

Tuberous Sclerosis Complex: Genes, Clinical Features and Therapeutics

Tuberous Sclerosis Complex: Genes, Clinical Features and Therapeutics

How to Cite

Kwiatkowski, D. J. (2010) Rat and Mouse Models of Tuberous Sclerosis, in Tuberous Sclerosis Complex: Genes, Clinical Features and Therapeutics (eds D. J. Kwiatkowski, V. H. Whittemore and E. A. Thiele), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527630073.ch7

Editor Information

  1. 1

    Brigham & Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, 1 Blackfan Circle, Boston, MA 02115, USA

  2. 2

    Tuberous Sclerosis Alliance, 801 Roeder Road, Silver Spring, MD 20910, USA

  3. 3

    Carol & James Herscot Center For TCS, Massachusetts General Hospital, Department of Neurology, 175 Cambridge Street, Boston, MA 02114, USA

Author Information

  1. Brigham & Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, 1 Blackfan Circle, Boston, MA 02115, USA

Publication History

  1. Published Online: 9 JUN 2010
  2. Published Print: 21 APR 2010

ISBN Information

Print ISBN: 9783527322015

Online ISBN: 9783527630073

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Keywords:

  • brain disease;
  • Eker rat;
  • glial fibrillary acidic protein;
  • hypomorphic allele;
  • rapamycin;
  • tuberous sclerosis mouse models of disease, TSC, TSC1, TSC2

Summary

This chapter contains sections titled:

  • Introduction

  • The Eker Rat

  • TSC Models in the Mouse

  • Concluding Remarks

  • References