7. Toxicological Interaction Thresholds of Chemical Mixtures

  1. Dr. Moiz Mumtaz
  1. Hisham El-Masri

Published Online: 28 DEC 2010

DOI: 10.1002/9783527630196.ch7

Principles and Practice of Mixtures Toxicology

Principles and Practice of Mixtures Toxicology

How to Cite

El-Masri, H. (2010) Toxicological Interaction Thresholds of Chemical Mixtures, in Principles and Practice of Mixtures Toxicology (ed M. Mumtaz), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527630196.ch7

Editor Information

  1. Agency for Toxic Substances and Disease Registry (ATSDR), Computational Toxicology and Methods, Development Laboratory, Division of Toxicology and Environmental Medicine, MS-F62, 1600 Clifton Road, Atlanta, GA 30333, USA

Author Information

  1. U.S. Environmental Protection Agency, National Health and Environmental, Effects Research Laboratory, Experimental Toxicology Division, 109 T.W. Alexander Drive, Mail Drop B143-01, Research Triangle Park, NC 27711, USA

Publication History

  1. Published Online: 28 DEC 2010
  2. Published Print: 25 AUG 2010

ISBN Information

Print ISBN: 9783527319923

Online ISBN: 9783527630196

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Keywords:

  • competitive inhibition;
  • dose-response relationship;
  • interaction mechanism;
  • interaction threshold;
  • NOAEL;
  • righting reflex;
  • single chemicals

Summary

This chapter contains sections titled:

  • Introduction

  • Statistical Analysis for Interaction Thresholds

  • Predictive Modeling of the Interaction Threshold

  • “No Interaction” Exposure Levels

  • References