Chapter 1. History of Industrial Biotechnology

  1. Prof. Wim Soetaert and
  2. Prof. Erick J. Vandamme
  1. Arnold L. Demain

Published Online: 29 APR 2010

DOI: 10.1002/9783527630233.ch1

Industrial Biotechnology: Sustainable Growth and Economic Success

Industrial Biotechnology: Sustainable Growth and Economic Success

How to Cite

Demain, A. L. (2010) History of Industrial Biotechnology, in Industrial Biotechnology: Sustainable Growth and Economic Success (eds W. Soetaert and E. J. Vandamme), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527630233.ch1

Editor Information

  1. Ghent University, Department of Biochemical and Microbial Technology, Centre of Expertise – Industrial Biotechnology and Biocatalysis, Faculty of Bioscience Engineering, Coupure links 653, 9000 Gent, Belgium

Author Information

  1. Drew University, Research Institute for Scientists Emeriti (R.I.S.E.), Madison, NJ 07940, USA

Publication History

  1. Published Online: 29 APR 2010
  2. Published Print: 21 APR 2010

ISBN Information

Print ISBN: 9783527314423

Online ISBN: 9783527630233

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Keywords:

  • penicillin;
  • drug development;
  • systems microbiology;
  • recombinant proteins;
  • biopharmaceutical revolution;
  • enzyme inhibitors

Summary

This chapter contains sections titled:

  • Early History

  • The Penicillin Story

  • The Coming of the Cephalosporins

  • The Waksman Era

  • Strain Improvement

  • Semi-Synthetic Antibiotics to Combat Resistant Microbes

  • The Primary Metabolites

  • The Shift from Antibiotics to Pharmacological Agents

  • The Biopharmaceutical Revolution

  • Recombinant Hosts

  • Enzymes

  • Bioconversions

  • Vaccines

  • Systems Microbiology

  • References