Chapter 4. Directed Evolution of Industrial Biocatalysts

  1. Prof. Wim Soetaert and
  2. Prof. Erick J. Vandamme
  1. Marlen Schmidt,
  2. Dominique Böttcher and
  3. Uwe T. Bornscheuer

Published Online: 29 APR 2010

DOI: 10.1002/9783527630233.ch4

Industrial Biotechnology: Sustainable Growth and Economic Success

Industrial Biotechnology: Sustainable Growth and Economic Success

How to Cite

Schmidt, M., Böttcher, D. and Bornscheuer, U. T. (2010) Directed Evolution of Industrial Biocatalysts, in Industrial Biotechnology: Sustainable Growth and Economic Success (eds W. Soetaert and E. J. Vandamme), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527630233.ch4

Editor Information

  1. Ghent University, Department of Biochemical and Microbial Technology, Centre of Expertise – Industrial Biotechnology and Biocatalysis, Faculty of Bioscience Engineering, Coupure links 653, 9000 Gent, Belgium

Author Information

  1. Greifswald University, Institute of Biochemistry, Department of Biotechnology and Enzyme Catalysis, Felix - Hausdorff - Str. 4, 17487 Greifswald, Germany

Publication History

  1. Published Online: 29 APR 2010
  2. Published Print: 21 APR 2010

ISBN Information

Print ISBN: 9783527314423

Online ISBN: 9783527630233

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Keywords:

  • rational protein design;
  • directed (molecular) evolution;
  • non-recombining evolution;
  • recombining evolution;
  • DNA or gene shuffling;
  • focused directed evolution

Summary

This chapter contains sections titled:

  • Introduction

  • Strategies for Protein Design

  • Assay Systems

  • Examples

  • Conclusions

  • References