Chapter 1. The Role of Copper Ion and the Ubiquitin System in Neurodegenerative Disorders
- Prof. Bruno Pignataro
Published Online: 9 JUN 2010
DOI: 10.1002/9783527630516.ch1
Copyright © 2010 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life
Additional Information
How to Cite
Arnesano, F. (2010) The Role of Copper Ion and the Ubiquitin System in Neurodegenerative Disorders, in Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life (ed B. Pignataro), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527630516.ch1
Editor Information
University of Palermo, Department of Physical Chemistry, Viale delle Scienze, 90128 Palermo, Italy
Publication History
- Published Online: 9 JUN 2010
- Published Print: 24 MAR 2010
ISBN Information
Print ISBN: 9783527325412
Online ISBN: 9783527630516
- Summary
- Chapter
- References
Keywords:
- ubiquitin;
- brain copper homeostasis;
- protofibrils;
- dehydrons;
- neurodegenerative disorders
Summary
This chapter contains sections titled:
Introduction
Metal Ions in the Brain
Brain Copper Homeostasis
Brain Copper and Neurodegenerative Disorders
The Role of Ubiquitin in Protein Degradation
Failure of the Ubiquitin System in Neurodegenerative Disorders
Interaction of Ubiquitin with Metal Ions
Biological Implications
Conclusions and Perspectives
Acknowledgments
References