Chapter 3. Chemical Protein Modification

  1. Prof. Bruno Pignataro
  1. Gonçalo J. L. Bernardes,
  2. Justin M. Chalker,
  3. Benjamin G. Davis

Published Online: 9 JUN 2010

DOI: 10.1002/9783527630516.ch3

Book Title

Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life

Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life

Additional Information

How to Cite

Bernardes, G. J. L., Chalker, J. M. and Davis, B. G. (2010) Chemical Protein Modification, in Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life (ed B. Pignataro), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527630516.ch3

Editor Information

  1. University of Palermo, Department of Physical Chemistry, Viale delle Scienze, 90128 Palermo, Italy

Author Information

  1. University of Oxford, Department of Chemistry, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom

Publication History

  1. Published Online: 9 JUN 2010
  2. Published Print: 24 MAR 2010

ISBN Information

Print ISBN: 9783527325412

Online ISBN: 9783527630516

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CHAPTER TOOLS

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Keywords:

  • posttranslational modification;
  • protein modification;
  • chemoselectivity;
  • aqueous reactions

Summary

This chapter contains sections titled:

  • Introducing Diversity by Posttranslational Modification

  • Chemistry: A Route to Modified Proteins

  • Challenges in Chemical Protein Modification

  • Traditional Methods for Protein Modification

  • Recent Innovations in Site-Selective Protein Modification

  • Conclusion and Outlook

  • References

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