Chapter 7. Structure-Based Design on the Way to New Anti-Infectives
- Prof. Bruno Pignataro
Published Online: 9 JUN 2010
DOI: 10.1002/9783527630516.ch7
Copyright © 2010 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life
Additional Information
How to Cite
Katharina Herta Hirsch, A. (2010) Structure-Based Design on the Way to New Anti-Infectives, in Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life (ed B. Pignataro), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527630516.ch7
Editor Information
University of Palermo, Department of Physical Chemistry, Viale delle Scienze, 90128 Palermo, Italy
Publication History
- Published Online: 9 JUN 2010
- Published Print: 24 MAR 2010
ISBN Information
Print ISBN: 9783527325412
Online ISBN: 9783527630516
- Summary
- Chapter
- References
Keywords:
- anti-infective agents;
- cocrystal structure analysis;
- kinase;
- nonmevalonate pathway;
- molecular recognition;
- structure-based inhibitor design
Summary
This chapter contains sections titled:
Introduction
Isoprenoids and the Nonmevalonate Pathway
Targeting the CDP-Binding Pocket of IspE
X-ray Cocrystal Structure Analysis
Conclusions and Outlook
Acknowledgments
List of Abbreviations
References