Chapter 9. Targeting Disease with Small Molecule Inhibitors of Protein–Protein Interactions

  1. Prof. Bruno Pignataro
  1. Fedor Forafonov,
  2. Elena Miranda,
  3. Ida Karin Nordgren and
  4. Ali Tavassoli

Published Online: 9 JUN 2010

DOI: 10.1002/9783527630516.ch9

Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life

Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life

How to Cite

Forafonov, F., Miranda, E., Karin Nordgren, I. and Tavassoli, A. (2010) Targeting Disease with Small Molecule Inhibitors of Protein–Protein Interactions, in Ideas in Chemistry and Molecular Sciences: Where Chemistry Meets Life (ed B. Pignataro), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527630516.ch9

Editor Information

  1. University of Palermo, Department of Physical Chemistry, Viale delle Scienze, 90128 Palermo, Italy

Author Information

  1. University of Southampton, School of Chemistry, University Road, Highfield, Southampton SO17 1BJ, United Kingdom

Publication History

  1. Published Online: 9 JUN 2010
  2. Published Print: 24 MAR 2010

ISBN Information

Print ISBN: 9783527325412

Online ISBN: 9783527630516

SEARCH

Keywords:

  • protein–protein interactions;
  • small molecule therapeutics;
  • high-throughput screening;
  • cyclic peptide inhibitors;
  • tumor hypoxia response network

Summary

This chapter contains sections titled:

  • Introduction

  • High-Throughput Screening of Chemical Libraries

  • High-Throughput Screening of Biosynthesized Libraries

  • Future Direction

  • Acknowledgments

  • References