Chapter 22. An Efficient, Asymmetric Synthesis of Odanacatib, a Selective Inhibitor of Cathepsin K for the Treatment of Osteoporosis, Using an Enzyme-Mediated Dynamic Kinetic Resolution

  1. Dr. Hans-Ulrich Blaser2 and
  2. Dr. Hans-Jürgen Federsel Director3
  1. Matthew D. Truppo

Published Online: 8 JUN 2010

DOI: 10.1002/9783527630639.ch22

Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions, Second Edition

Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions, Second Edition

How to Cite

Truppo, M. D. (2010) An Efficient, Asymmetric Synthesis of Odanacatib, a Selective Inhibitor of Cathepsin K for the Treatment of Osteoporosis, Using an Enzyme-Mediated Dynamic Kinetic Resolution, in Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions, Second Edition (eds H.-U. Blaser and H.-J. Federsel), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527630639.ch22

Editor Information

  1. 2

    Solvias AG, P.O. Box, CH-4002, Basel, Switzerland

  2. 3

    AstraZeneca, 151 85 Södertälje, Sweden

Author Information

  1. Merck & Co., Inc., Department of Process Research, Merck Research Laboratories, Rahway, NJ 07065, USA

Publication History

  1. Published Online: 8 JUN 2010
  2. Published Print: 19 MAY 2010

ISBN Information

Print ISBN: 9783527324897

Online ISBN: 9783527630639

SEARCH

Options for accessing this content:

  • If you have access to this content through a society membership, please first log in to your society website.
  • Login via other institutional login options http://onlinelibrary.wiley.com/login-options.
  • You can purchase online access to this Chapter for a 24-hour period (price varies by title)
    • If you already have a Wiley Online Library or Wiley InterScience user account: login above and proceed to purchase the article.
    • New Users: Please register, then proceed to purchase the article.

Type your institution's name in the box below. If your institution is a Wiley customer, it will appear in the list of suggested institutions and you will be able to log in to access content. Some users may also log in directly via OpenAthens.

Please note that there are currently a number of duplicate entries in the list of institutions. We are actively working on fixing this issue and apologize for any inconvenience caused.

Please register to:

  • Save publications, articles and searches
  • Get email alerts
  • Get all the benefits mentioned below!

Register now >