18. Gonadotropins and Progestogens: Obligatory Developmental Functions during Early Embryogenesis and their Role in Adult Neurogenesis, Neuroregeneration and Neurodegeneration

  1. Prof. Dr. Achille G. Gravanis3 and
  2. Prof. Dr. Synthia H. Mellon4
  1. Craig S. Atwood1 and
  2. Sivan Vadakkadath Meethal2

Published Online: 2 FEB 2011

DOI: 10.1002/9783527633968.ch18

Hormones in Neurodegeneration, Neuroprotection, and Neurogenesis

Hormones in Neurodegeneration, Neuroprotection, and Neurogenesis

How to Cite

Atwood, C. S. and Meethal, S. V. (2011) Gonadotropins and Progestogens: Obligatory Developmental Functions during Early Embryogenesis and their Role in Adult Neurogenesis, Neuroregeneration and Neurodegeneration, in Hormones in Neurodegeneration, Neuroprotection, and Neurogenesis (eds A. G. Gravanis and S. H. Mellon), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527633968.ch18

Editor Information

  1. 3

    University of Crete, Department of Pharmacology, School of Medicine, Stavrakia, 71110 Heraklion, Greece

  2. 4

    University of California, Department of Obstetrics, Gynecology, and Reproductive Sciences, The Center for Reproductive Sciences, 513 Parnassus Avenue, San Francisco, CA 94143, USA

Author Information

  1. 1

    Department of Medicine, University of Wisconsin-Madison, School of Medicine and Public, Health and Geriatric Research, Education and Clinical Center, Veterans administration Hospital, 2500 Overlook Terrace, Madison, WI 53705, USA

  2. 2

    University of Wisconsin-Madison, Department of Neurological Surgery, School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA

Publication History

  1. Published Online: 2 FEB 2011
  2. Published Print: 14 JAN 2011

ISBN Information

Print ISBN: 9783527326273

Online ISBN: 9783527633968

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Keywords:

  • human embryonic stem cell;
  • opioid;
  • progesterone;
  • embryoid body;
  • rosette;
  • nestin;
  • neural precursor cell;
  • antagonist;
  • RU-486;
  • ICI 174;
  • 864;
  • neurodegeneration;
  • Alzheimer's disease;
  • stroke;
  • human chorionic gonadotropin;
  • embryogenesis;
  • blastulation;
  • neurulation;
  • progestins;
  • hormone;
  • pregnancy;
  • germ layers;
  • trophoblast;
  • endocrine;
  • juxtacrine;
  • paracrine;
  • zygote;
  • morula;
  • endorphins;
  • 17β-estradiol;
  • gonadotropin-releasing hormone;
  • cell lineage;
  • cell division;
  • differentiation;
  • sex steroids;
  • neurosteroids;
  • LH receptor;
  • progesterone receptor;
  • cell cycle;
  • aging;
  • blood–brain barrier;
  • AβPP;
  • Aβ opioid;
  • opioid receptor;
  • brain

Summary

This chapter contains sections titled:

  • Introduction

  • Hormonal Regulation of Human Embryogenesis

  • Progesterone: an Essential Neurotrophic Hormone during All Phases of Life

  • Age-Related Loss of Progesterone: Implications in the Pathophysiology of Neurodegenerative Diseases

  • Conclusion

  • References