7. Neuroactive Steroids and Peripheral Neuropathy

  1. Prof. Dr. Achille G. Gravanis4 and
  2. Prof. Dr. Synthia H. Mellon5
  1. Roberto C. Melcangi1,
  2. Silvia Giatti1,
  3. Marzia Pesaresi1,
  4. Donatella Caruso2 and
  5. Marc J. Tetel3

Published Online: 2 FEB 2011

DOI: 10.1002/9783527633968.ch7

Hormones in Neurodegeneration, Neuroprotection, and Neurogenesis

Hormones in Neurodegeneration, Neuroprotection, and Neurogenesis

How to Cite

Melcangi, R. C., Giatti, S., Pesaresi, M., Caruso, D. and Tetel, M. J. (2011) Neuroactive Steroids and Peripheral Neuropathy, in Hormones in Neurodegeneration, Neuroprotection, and Neurogenesis (eds A. G. Gravanis and S. H. Mellon), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527633968.ch7

Editor Information

  1. 4

    University of Crete, Department of Pharmacology, School of Medicine, Stavrakia, 71110 Heraklion, Greece

  2. 5

    University of California, Department of Obstetrics, Gynecology, and Reproductive Sciences, The Center for Reproductive Sciences, 513 Parnassus Avenue, San Francisco, CA 94143, USA

Author Information

  1. 1

    University of Milan, Department of Endocrinology, Pathophysiology and applied Biology, Via Balzaretti 9, 20133 Milano, Italy

  2. 2

    University of Milan, Department of Pharmacological Sciences, Via Balzaretti 9, 20133 Milano, Italy

  3. 3

    Wellesley College, Neuroscience Program, 106 Central St., Wellesley, MA 02481, USA

Publication History

  1. Published Online: 2 FEB 2011
  2. Published Print: 14 JAN 2011

ISBN Information

Print ISBN: 9783527326273

Online ISBN: 9783527633968

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Keywords:

  • progesterone;
  • testosterone;
  • 5α-reductase;
  • tetrahydroprogesterone;
  • Schwann cell;
  • sciatic nerve;
  • SRC-1;
  • steroid receptor

Summary

This chapter contains sections titled:

  • Introduction

  • Regulation of Neuroactive Steroid Responsiveness in Peripheral Nerves

  • Schwann Cell Responses to Neuroactive Steroids

  • Sexually Dimorphic Changes of Neuroactive Steroid Levels Induced by Pathology in Peripheral Nerves

  • Neuroactive Steroids as Protective Agents in PNS

  • Chemotherapy-Induced Peripheral Neuropathy

  • Concluding Remarks

  • Acknowledgments

  • References