20. Modifications of Optical Properties of Blood during Photodynamic Reactions In vitro and In vivo

  1. Prof. Valery V. Tuchin5,6
  1. Alexandre Douplik1,2,
  2. Alexander Stratonnikov3,
  3. Olga Zhernovaya4 and
  4. Viktor Loshchenov3

Published Online: 5 APR 2011

DOI: 10.1002/9783527634286.ch20

Advanced Optical Flow Cytometry: Methods and Disease Diagnoses

Advanced Optical Flow Cytometry: Methods and Disease Diagnoses

How to Cite

Douplik, A., Stratonnikov, A., Zhernovaya, O. and Loshchenov, V. (2011) Modifications of Optical Properties of Blood during Photodynamic Reactions In vitro and In vivo, in Advanced Optical Flow Cytometry: Methods and Disease Diagnoses (ed V. V. Tuchin), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527634286.ch20

Editor Information

  1. 5

    Saratov State University, Optics and Biophotonics, Department and Research-Educational Institute of Optics and Biophotonics, 83 Astrakhanskaya St., Saratov 410012, Russia

  2. 6

    Laboratory on Laser Diagnostics of Technical and Living Systems, Institute of Precise Mechanics and Control of RAS, 24, Rabochaya st., Saratov 410028, Russia

Author Information

  1. 1

    Clinical Photonics Lab at Erlangen Graduate School in Advanced Optical Technologies (SAOT), Friedrich-Alexander Universität, Erlangen-Nürnberg, Erlangen, Germany

  2. 2

    Medical Photonics Engineering at Chair of Photonics Technologies, Friedrich-Alexander Universität, Erlangen-Nürnberg, Erlangen, Germany

  3. 3

    General Physics Institute, Russian Academy of Science, Moscow, Russia

  4. 4

    International Research-Educational Center of Optical Technologies for Industry and Medicine “Photonics”, Saratov State University, Saratov, Russia

Publication History

  1. Published Online: 5 APR 2011
  2. Published Print: 20 APR 2011

ISBN Information

Print ISBN: 9783527409341

Online ISBN: 9783527634286

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Keywords:

  • photodynamic therapy (PDT);
  • photodynamic antimicrobial chemotherapy (PACT);
  • photochemical reactions;
  • photosensitizers;
  • laser tissue interaction;
  • blood;
  • blood cells;
  • blood pigments;
  • blood optical properties;
  • blood oxygenation;
  • singlet oxygen;
  • oxygen consumption

Summary

This chapter contains sections titled:

  • Introduction

  • Description and Brief History of PDT

  • PDT Mechanisms

  • Blood and PDT

  • Properties of Blood, Blood Cells, and Photosensitizers: Before Photodynamic Reaction

  • Photodynamic Reactions in Blood and Blood Cells, Blood Components, and Cells

  • Types of Photodynamic Reactions in Blood: In vitro versus In vivo

  • Blood Sample In vitro as a Model Studying Photodynamic Reaction

  • Monitoring of Oxygen Consumption and Photobleaching in Blood during PDT In vivo

  • Photodynamic Disinfection of Blood

  • Photodynamic Therapy of Blood Cell Cancer

  • Summary

  • Acknowledgments

  • Glossary

  • References