14. Omics in Cancer Risk Assessment: Pathways to Disease

  1. Prof. Dr. Günter Obe3,4,
  2. Dr. Burkhard Jandrig5,
  3. Prof. Dr. Gary E. Marchant6,
  4. Dipl. Päd. Holger Schütz7 and
  5. Prof. Dr. Peter M. Wiedemann8
  1. Christopher J. Portier1 and
  2. Reuben Thomas2

Published Online: 27 APR 2011

DOI: 10.1002/9783527634613.ch14

Cancer Risk Evaluation: Methods and Trends

Cancer Risk Evaluation: Methods and Trends

How to Cite

Portier, C. J. and Thomas, R. (2011) Omics in Cancer Risk Assessment: Pathways to Disease, in Cancer Risk Evaluation: Methods and Trends (eds G. Obe, B. Jandrig, G. E. Marchant, H. Schütz and P. M. Wiedemann), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527634613.ch14

Editor Information

  1. 3

    Ret. from University Duisburg-Essen, Germany

  2. 4

    Gershwinstrasse 33, 14513 Teltow, Germany

  3. 5

    Max-Delbrück-Center for Molecular Medicine (MDC), Robert-Rössle-Str. 10, 13125 Berlin, Germany

  4. 6

    Arizona State University, Sandra Day O'Connor College of Law, P.O. Box 877906, Tempe, AZ 85287-796, USA

  5. 7

    Research Center Jülich, Institute of Neuroscience and Medicine (INM-8), 52425 Jülich, Germany

  6. 8

    Karlsruher Institut für Technologie (KIT), TAB – Büro für Technikfolgen-Abschätzung beim Deutschen Bundestag, Neue Schönhauser Straße 10, 10178 Berlin, Germany

Author Information

  1. 1

    National Center for Environmental Health/Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA

  2. 2

    National Institute of Environmental Health Sciences, Laboratory of Toxicology and Pharmacology, Environmental Systems Biology, P.O. Box 12233, MD B2-08, Research Triangle Park, NC 27709, USA

Publication History

  1. Published Online: 27 APR 2011
  2. Published Print: 20 APR 2011

ISBN Information

Print ISBN: 9783527327539

Online ISBN: 9783527634613



  • cancer risk assessment;
  • carcinogenicity;
  • genomics;
  • low-dose extrapolation;
  • parallelogram;
  • structurally enhanced pathway enrichment analysis


This chapter contains sections titled:

  • Introduction

  • “Omics” Data in Cancer Risk Assessment

  • High-Throughput Screening

  • Discussion

  • References