1. Peptides as Leads for Drug Discovery

  1. Prof. Dr. Miguel Castanho and
  2. Prof. Dr. Nuno C. Santos
  1. Paul J. Edwards1 and
  2. Steven R. LaPlante2

Published Online: 17 OCT 2011

DOI: 10.1002/9783527636730.ch1

Peptide Drug Discovery and Development: Translational Research in Academia and Industry

Peptide Drug Discovery and Development: Translational Research in Academia and Industry

How to Cite

Edwards, P. J. and LaPlante, S. R. (2011) Peptides as Leads for Drug Discovery, in Peptide Drug Discovery and Development: Translational Research in Academia and Industry (eds M. Castanho and N. C. Santos), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527636730.ch1

Editor Information

  1. University of Lisbon, Institute of Biochemistry, Av. Egas Moniz, 1649-028 Lisboa, Portugal

Author Information

  1. 1

    Boehringer Ingelheim (Canada) Ltd, Research & Development, 2100 Rue Cunard, Laval, QC, H7S 3G5, Canada

  2. 2

    Boehringer Ingelheim (Canada) Ltd, Research & Development, 2100 Rue Cunard, Laval, QC, H7S 2G5, Canada

Publication History

  1. Published Online: 17 OCT 2011
  2. Published Print: 5 OCT 2011

ISBN Information

Print ISBN: 9783527328918

Online ISBN: 9783527636730

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Keywords:

  • bioactive conformation;
  • rational drug design;
  • peptidomimetics;
  • NMR;
  • medicinal chemistry;
  • ligand dynamics

Summary

This chapter contains sections titled:

  • Introduction

  • Overview of Process for Transforming Peptides to Peptidomimetics

  • HCMV Protease

  • HCV Protease

  • Herpes Simplex Virus

  • Renin

  • HIV

  • Conclusions