14. Of Mice and Men: Translational Research on Amylin Agonism

  1. Prof. Dr. Miguel Castanho and
  2. Prof. Dr. Nuno C. Santos
  1. Jonathan D. Roth,
  2. Christine M. Mack,
  3. James L. Trevaskis and
  4. David G. Parkes

Published Online: 17 OCT 2011

DOI: 10.1002/9783527636730.ch14

Peptide Drug Discovery and Development: Translational Research in Academia and Industry

Peptide Drug Discovery and Development: Translational Research in Academia and Industry

How to Cite

Roth, J. D., Mack, C. M., Trevaskis, J. L. and Parkes, D. G. (2011) Of Mice and Men: Translational Research on Amylin Agonism, in Peptide Drug Discovery and Development: Translational Research in Academia and Industry (eds M. Castanho and N. C. Santos), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527636730.ch14

Editor Information

  1. University of Lisbon, Institute of Biochemistry, Av. Egas Moniz, 1649-028 Lisboa, Portugal

Author Information

  1. Amylin Pharmaceuticals Inc., 9360 Towne Centre Drive, CA 92121 San Diego, USA

Publication History

  1. Published Online: 17 OCT 2011
  2. Published Print: 5 OCT 2011

ISBN Information

Print ISBN: 9783527328918

Online ISBN: 9783527636730

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Keywords:

  • amylin;
  • pramlintide;
  • obesity;
  • β-cell hormone;
  • diabetes;
  • combination therapy

Summary

This chapter contains sections titled:

  • Overview of Amylin Physiology

  • Pramlintide: An Amylin Agonist

  • Amylin Agonism: Translational Research in Insulin-Dependent Diabetes

  • Amylin Agonism: Translational Research in Obesity