5. Polymer MALDI Sample Preparation

  1. Prof. Dr. Christopher Barner-Kowollik3,
  2. Dr. Till Gruendling3,
  3. Dr. Jana Falkenhagen4 and
  4. Dr. Steffen Weidner4
  1. Scott D. Hanton1 and
  2. Kevin G. Owens2

Published Online: 2 JAN 2012

DOI: 10.1002/9783527641826.ch5

Mass Spectrometry in Polymer Chemistry

Mass Spectrometry in Polymer Chemistry

How to Cite

Hanton, S. D. and Owens, K. G. (2011) Polymer MALDI Sample Preparation, in Mass Spectrometry in Polymer Chemistry (eds C. Barner-Kowollik, T. Gruendling, J. Falkenhagen and S. Weidner), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527641826.ch5

Editor Information

  1. 3

    Karlsruhe Institute of Technology (KIT), Institut für Technische Chemie und Polymerchemie, Macromolecular Chemistry, Engesserstr. 18, 76128 Karlsruhe, Germany

  2. 4

    Bundesanstalt für Materialforschung und -prüfung (BAM), Federal Institute for Materials Research and Testing, Richard-Willstätter-Strasse 11, 12489 Berlin, Germany

Author Information

  1. 1

    Intertek ASA, 7201 Hamilton Blvd. RD1, Dock #5, Allentown, PA 18195, USA

  2. 2

    Drexel University, Chemistry Department, 3141 Chestnut Street, Philadelphia, PA 19104, USA

Publication History

  1. Published Online: 2 JAN 2012
  2. Published Print: 7 DEC 2011

ISBN Information

Print ISBN: 9783527329243

Online ISBN: 9783527641826

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Keywords:

  • matrix-assisted laser desorption ionization (MALDI);
  • matrix to analyte ratio;
  • laser desorption (LD);
  • time-of-flight mass spectrometers (TOFMS);
  • polymer analytes;
  • salt to analyte ratio;
  • sample preparation;
  • solvent-free;
  • vortex method

Summary

This chapter contains sections titled:

  • Introduction

  • Roles of the Matrix

  • Choice of Matrix

  • Choice of the Solvent

  • Basic Solvent-Based Sample Preparation Recipe

  • Deposition Methods

  • Solvent-Free Sample Preparation

  • The Vortex Method

  • Matrix-to-Analyte Ratio

  • Salt-to-Analyte Ratio

  • Chromatography as Sample Preparation

  • Problems in MALDI Sample Preparation

  • Predicting MALDI Sample Preparation

  • Conclusions

  • References