20. Microwave-Enhanced Synthesis of Peptides, Proteins, and Peptidomimetics

  1. Prof. Antonio de la Hoz2 and
  2. Dr. André Loupy3
  1. Jonathan M. Collins

Published Online: 27 FEB 2013

DOI: 10.1002/9783527651313.ch20

Microwaves in Organic Synthesis, Volume 1, Third Edition

Microwaves in Organic Synthesis, Volume 1, Third Edition

How to Cite

Collins, J. M. (2012) Microwave-Enhanced Synthesis of Peptides, Proteins, and Peptidomimetics, in Microwaves in Organic Synthesis, Volume 1, Third Edition (eds A. de la Hoz and A. Loupy), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527651313.ch20

Editor Information

  1. 2

    Universidad de Castilla-La Mancha, Facultad de Ciencias y, Technologías Químicas, Avda. Camilo Josè Cela 10, 13071 Ciudad Real, Spain

  2. 3

    Universitè Paris-Sud 11, Laboratoire des Réactions, Sélectives sur Supports, Laboratoire de Chimie des, procédés et Substances Naturelles, ICMMO, Bâtiment 410, 91405 Orsay, France

Author Information

  1. CEM Corporation, 3100 Smith Farm Road, Matthews, NC 28104, USA

Publication History

  1. Published Online: 27 FEB 2013
  2. Published Print: 5 DEC 2012

ISBN Information

Print ISBN: 9783527331161

Online ISBN: 9783527651313

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Keywords:

  • peptides;
  • proteins;
  • peptidomimetics;
  • microwave-enhanced synthesis;
  • amide bond formation;
  • resin cleavage

Summary

This chapter contains sections titled:

  • Introduction

  • Synthesis Approaches

  • Microwave Theory for Peptide Synthesis

  • Nα-Amino Protection Strategies

  • Amide Bond Formation

  • Modified Peptides

  • Non-Natural Peptidomimetics

  • Resin Cleavage

  • Recommended Protocols

  • Conclusion

  • Abbreviations

  • Acknowledgment

  • References