12. Modeling and Experimental Model Parameter Determination with Quality by Design for Bioprocesses

  1. Dr. Ganapathy Subramanian
  1. Christoph Helling and
  2. Jochen Strube

Published Online: 15 OCT 2012

DOI: 10.1002/9783527653096.ch12

Biopharmaceutical Production Technology, Volume 1 & Volume 2

Biopharmaceutical Production Technology, Volume 1 & Volume 2

How to Cite

Helling, C. and Strube, J. (2012) Modeling and Experimental Model Parameter Determination with Quality by Design for Bioprocesses, in Biopharmaceutical Production Technology, Volume 1 & Volume 2 (ed G. Subramanian), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527653096.ch12

Editor Information

  1. 44 Oaken Grove, Maidenhead, Berkshire SL6 6HH, United Kingdom

Author Information

  1. Clausthal University of Technology, Institute for Separation and Process Technology, Leibnizstrasse 15, 38678 Clausthal-Zellerfeld, Germany

Publication History

  1. Published Online: 15 OCT 2012
  2. Published Print: 18 JUL 2012

ISBN Information

Print ISBN: 9783527330294

Online ISBN: 9783527653096

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Keywords:

  • quality by design;
  • bioprocess;
  • modeling;
  • parameter;
  • robustness;
  • separation

Summary

This chapter contains sections titled:

  • Introduction

  • QbD Fundamentals

  • Process Modeling and Experimental Model Parameter Determination

  • Process Robustness Study

  • Conclusions

  • Nomenclature

  • Acknowledgments

  • References