7. The Oligomer Species: Mechanistics and Biochemistry

  1. Prof. Dr. Daniel Erik Otzen
  1. Massimo Stefani1,2

Published Online: 27 JAN 2013

DOI: 10.1002/9783527654185.ch7

Amyloid Fibrils and Prefibrillar Aggregates: Molecular and Biological Properties

Amyloid Fibrils and Prefibrillar Aggregates: Molecular and Biological Properties

How to Cite

Stefani, M. (2013) The Oligomer Species: Mechanistics and Biochemistry, in Amyloid Fibrils and Prefibrillar Aggregates: Molecular and Biological Properties (ed D. E. Otzen), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527654185.ch7

Editor Information

  1. Aarhus University, iNANO (Interdisciplinary Nanoscience Center), Department of Molecular Biology and Genetics, Center for Insoluble Protein Structures (inSPIN), Gustav Wieds Vej 14, 8000 Aarhus, Denmark

Author Information

  1. 1

    University of Florence, Department of Biochemical Sciences, Viale Morgagni 50, 50134 Florence, Italy

  2. 2

    Research Centre on the Molecular Basis of Neurodegeneration, Istituto Nazionale di Biostrutture e Biosistemi, INBB, Viale Morgagni 50, 50134 Florence, Italy

Publication History

  1. Published Online: 27 JAN 2013
  2. Published Print: 12 FEB 2013

ISBN Information

Print ISBN: 9783527332007

Online ISBN: 9783527654185

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Keywords:

  • amyloid oligomer;
  • structure–toxicity relation of amyloids;
  • oligomer;
  • cytotoxicity;
  • oligomer–membrane complex;
  • amyloid pores;
  • amyloid cascade

Summary

This chapter contains sections titled:

  • Introduction

  • The Structure–Toxicity Relation of Early Amyloids

  • The Oligomer–Membrane Complex

  • Biochemical Modifications Underlying Amyloid Toxicity

  • Summary

  • References