21. Single-Molecule Spectroscopy

  1. Prof. Dr. Günter Gauglitz4 and
  2. Dr. David S. Moore5
  1. Frank Schleifenbaum1,
  2. Christian Blum2,
  3. Marc Brecht3 and
  4. Alfred J. Meixner3

Published Online: 2 APR 2014

DOI: 10.1002/9783527654703.ch21

Handbook of Spectroscopy: Second, Enlarged Edition

Handbook of Spectroscopy: Second, Enlarged Edition

How to Cite

Schleifenbaum, F., Blum, C., Brecht, M. and Meixner, A. J. (2014) Single-Molecule Spectroscopy, in Handbook of Spectroscopy: Second, Enlarged Edition (eds G. Gauglitz and D. S. Moore), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527654703.ch21

Editor Information

  1. 4

    University of Tübingen, Institute for Physical and Theoretical Chemistry, Auf der Morgenstelle 18, 72076 Tübingen, Germany

  2. 5

    Los Alamos National Laboratory, Shock and Detonation Physics Group, MS-P952, Los Alamos, NM 87545, USA

Author Information

  1. 1

    University of Tuebingen, Center of Plant Molecular Biology (ZMBP), Biophysical Chemistry, Auf der Morgenstelle 8, 72076, Tuebingen, Germany

  2. 2

    University of Twente, Nanobiophysics, MESA + Institute for Nanotechnology, PO Box 217, 7500AE, Enschede, The Netherlands

  3. 3

    University of Tuebingen, Institute of Physical and Theoretical Chemistry, Auf der Morgenstelle 8, 72076, Tuebingen, Germany

Publication History

  1. Published Online: 2 APR 2014
  2. Published Print: 23 APR 2014

ISBN Information

Print ISBN: 9783527321506

Online ISBN: 9783527654703

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Keywords:

  • single-molecule spectroscopy;
  • low temperature;
  • SERS;
  • Raman;
  • fluorescence;
  • Fabry–Perot;
  • quantum control

Summary

Single-molecule spectroscopy has become a major tool to investigate molecular properties with an outstanding sensitivity. Moreover, ensemble averaging, which is inevitable in any other techniques, is circumvented by these techniques. Thus, fascinating insights into the interaction of a single molecule with its chemical nano-environment are obtained. Moreover, a deeper understanding of complex molecular structures such as biological macromolecules can be achieved. In this chapter, a comprehensive overview of the development of the single-molecule techniques from the beginning in the early 1990s until recent achievements is provided.