1. Proline-Related Secondary Amine Catalysts and Applications

  1. Peter I. Dalko
  1. Hiyoshizo Kotsuki and
  2. Niiha Sasakura

Published Online: 23 AUG 2013

DOI: 10.1002/9783527658862.ch1

Comprehensive Enantioselective Organocatalysis: Catalysts, Reactions, and Applications

Comprehensive Enantioselective Organocatalysis: Catalysts, Reactions, and Applications

How to Cite

Kotsuki, H. and Sasakura, N. (2013) Proline-Related Secondary Amine Catalysts and Applications, in Comprehensive Enantioselective Organocatalysis: Catalysts, Reactions, and Applications (ed P. I. Dalko), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527658862.ch1

Editor Information

  1. Université Paris-Descartes, PRES Sorbonne Paris Cité, CNRS, 45, rue des Saints-Pères, 75270 Paris Cedex 06, France

Publication History

  1. Published Online: 23 AUG 2013
  2. Published Print: 23 OCT 2013

ISBN Information

Print ISBN: 9783527332366

Online ISBN: 9783527658862

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Keywords:

  • asymmetric synthesis;
  • catalyst design;
  • organocatalysis;
  • proline-related catalyst;
  • pyrrolidine catalyst

Summary

Organocatalytic asymmetric synthesis has been extensively studied and several important methods for preparing optically active organic compounds have been developed. Research in this area has seen rapid progress over the past decade. This chapter addresses the major advances in asymmetric synthesis using proline-related organocatalysts, mainly from the viewpoint of catalyst design and synthetic applications. These catalysts include (i) prolinamides, (ii) prolinamines, (iii) proline tetrazoles, (iv) prolinamine sulfonamides, (v) prolinamine thioureas, and (vi) miscellaneous.