Generating New Molecular Function: A Lesson from Nature

  1. Prof. Gerhard Quinkert2 and
  2. Dr. M. Volkan Kisakürek3
  1. David R. Liu and
  2. Peter G. Schultz

Published Online: 3 MAY 2007

DOI: 10.1002/9783906390451.ch10

Essays in Contemporary Chemistry: From Molecular Structure towards Biology

Essays in Contemporary Chemistry: From Molecular Structure towards Biology

How to Cite

Liu, D. R. and Schultz, P. G. (2001) Generating New Molecular Function: A Lesson from Nature, in Essays in Contemporary Chemistry: From Molecular Structure towards Biology (eds G. Quinkert and M. V. Kisakürek), Verlag Helvetica Chimica Acta, Zürich. doi: 10.1002/9783906390451.ch10

Editor Information

  1. 2

    Institut für Organische Chemie, Johann Wolfgang Goethe-Universität, Marie Curie-Str. 11, D-60439 Frankfurt am Main, Germany

  2. 3

    Verlag Helvetica Chimica Acta, Hofwiesenstrasse 26, Postfach, CH-8042 Zürich, Switzerland

Author Information

  1. Howard Hughes Medical Institute and Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720-1460, USA

  1. This essay is based on a lecture delivered at the 36th IUPAC Congress in Geneva, 1997.

Publication History

  1. Published Online: 3 MAY 2007
  2. Published Print: 13 SEP 2001

ISBN Information

Print ISBN: 9783906390284

Online ISBN: 9783906390451

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Keywords:

  • generation of new molecular function;
  • libraries of biomolecules

Summary

The development of strategies for generating large diverse libraries of biomolecules, small organic molecules, and solid-state materials, together with novel screens and selections for specific biological, chemical, or physical properties, is having an enormous impact on science. These approaches are significantly increasing the rate and efficiency with which the scientific method can be used both to identify molecules with novel properties and to understand the structural basis for their function.